Department of Chemistry

The Department of Chemistry at the Technical University of Munich has taken great efforts to meet the requirements of a rapidly changing scientific environment.
We offer a broad diversity of subjects: The traditional areas of Inorganic Chemistry, Organic Chemistry, and Physical Chemistry have been enriched by Chemical Technology, Radiochemistry, Food Chemistry, Theoretical Chemistry, and Hydrochemistry many years ago. The last years saw new expansions into the fields of Biochemistry and Construction Chemistry.

Secure nano-carrier delivers medications directly to cells

Nanoparticles with synthetic DNA can control release of drugs

[25.09.2020] Medications often have unwanted side-effects. One reason is that they reach not only the unhealthy cells for which they are intended, but also reach and have an impact on healthy cells. Researchers at the Technical University of Munich (TUM), working together with the KTH Royal Institute of Technology in Stockholm, have developed a stable nano-carrier for medications. A special mechanism makes sure the drugs are only released in diseased cells. [more...]

Substrate dynamics governs recognition by \(\gamma\)-secretase

Novel recognition mechanism of \(\gamma\)-secretase revealed for the Alzheimer risk factor TREM2

[10.09.2020] A research team from the Technical University of Munich at the Department of Chemistry led by biochemist Franz Hagn together with colleagues at the LMU and the German Center for Neurodegenerative Diseases (DZNE) around Christian Haass provide unprecedented structural insights into the mechanism of substrate recognition of the Alzheimer disease risk factor TREM2 by the intra-membrane protease \(\gamma\)-secretase. [more...]