Research Areas

Prof. Reif’s (b. 1968) group examines the structure of membrane proteins and amyloid fibrils using MAS (magic angle spinning) solid-state NMR spectroscopy. Research is focused on aggregates of the Alzheimer’s beta amyloid peptide. NMR experiments help to determine the binding site of small molecules. This work is highly significant in terms of diagnosis and treatment. Methodical new approaches are developed to gather information on the structure and dynamics of uniform isotope-labeled proteins in the solid phase.