Research Highlights

New Insights into the Maturation of miRNAs

The protein (blue) recognizes the pri-miR18a (pink) and transforms it into the mature miRNA. (Image: H. Kooshapur / TUM)

Elucidating the maturation mechanism of a cancer-causing microRNA

[03.07.2018] An international research team has used a structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation. In the future, the authors hope to develop new therapies based on their findings. [more...]

Bayerischer Verdienstorden geht drei Mal an die TUM

Prof. Günther Wess, Honorarprofessor an der TUM und Wissenschaftlicher Geschäftsführer des Helmholtz Zentrum München wurde ebenfalls mit dem Bayerischen Verdienstorden geehrt. (Bild: Bayerische Staatskanzlei)

Chris-Carolin Schön, Johannes B. Ortner und Günther Wess ausgezeichnet

[27.06.2018] Ministerpräsident Dr. Markus Söder hat drei Angehörige der Technischen Universität München (TUM) mit dem Bayerischen Verdienstorden ausgezeichnet: Prof. Chris-Carolin Schön vom Lehrstuhl für Pflanzenzüchtung, Johannes B. Ortner, Ehrensenator der TUM, und Prof. Günther Wess, Honorarprofessor in der Fakultät für Chemie, erhielten die Ehrung, die jährlich für herausragende Verdienste um den Freistaat Bayern verliehen wird. [mehr...]

 

 

Organic insect deterrent for agriculture

If aphids have the choice between wheat seedlings with (right) and without CBT-ol treatment (left), they avoid the treated seedlings. (Images: W. Mischko / TUM)

Biodegradable crop protection products without risks or side effects

[06.06.2018] Traditional insecticides are killers: they not only kill pests, they also endanger bees and other beneficial insects, as well as affecting biodiversity in soils, lakes, rivers and seas. A team from the Technical University of Munich (TUM) has now developed an alternative: A biodegradable agent that keeps pests at bay without poisoning them. [more...]

New tool for battery research

TUM President Prof. W.A. Herrmann, Dr. Michael Metzger and Dr. Marcus Morawietz, Managing Director at Strategy&, (fltr) at the Technical University of Munich (Photo: Andreas Battenberg / TUM)

Strategy& Presidential Award for lithium-ion battery test cell with separate electrodes

[21.05.2018] For a long time it was nearly impossible to examine the reactions at the anode and the cathode of lithium-ion batteries separately. As part of his doctoral thesis, Michael Metzger, scientist at the Chair of Technical Electrochemistry of the Technical University of Munich (TUM), developed an innovative battery test cell, which can do just that. For his innovative work, he was awarded the Strategy & Presidential Award 2017. [more...]

In the beginning was the phase separation

Left: clear solution, right: aqueous solution, clouded by ultrafine oil droplets. (Picture: A. Battenberg / TUM)

A simple mechanism could have been decisive for the development of life

[23.05.2018] The question of the origin of life remains one of the oldest unanswered scientific questions. A team at the Technical University of Munich (TUM) has now shown for the first time that phase separation is an extremely efficient way of controlling the selection of chemical building blocks and providing advantages to certain molecules. [more...]

Dirk Busch and Michael Sattler become members of Leopoldina

Prof. Dirk Busch and Prof. Michael Sattler. (Image: A. Heddergott and A. Eckert / TUM)

German National Academy of Sciences awards membership to two scientists from the TUM

[21.05.2018] The German National Academy of Sciences Leopoldina has appointed a medical scientist and a chemist from the Technical University of Munich as new members: Prof. Dirk Busch, Professor of Medical Microbiology, Immunology and Hygiene, and Prof. Michael Sattler, Professor of Biomolecular NMR Spectroscopy. They will receive their certificate of membership at the annual symposium of Class II – Life Sciences on 23 May 2018. [more...]

Deadly duet

Single subunits of YaxA (blue) and YaxB (purple) and a pore built up from these subunits. Image: Bastian Bräuning / TUM

Research team uncovers mechanism of action for a class of bacterial toxins

[07.05.2018] Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the mechanism of action for one of these toxins. The findings could help combat associated diseases and advance crop protection. [more...]

The enzyme designers

Sophie Mader and Prof. Ville Kaila; on the screens the simulation of the two AsqJ variants. (Image: A. Battenberg / TUM)

Simulation of the AsqJ enzyme opens up new options for pharmaceutical chemistry

[17.04.2018] Practically all biochemical processes involve enzymes that accelerate chemical reactions. A research team from the Technical University of Munich (TUM) has now for the first time deciphered the molecular mechanism of the enzyme AsqJ. Their findings might open up new options in the production of pharmaceutically active molecules. [more...]

Measurement chip detects Legionella

First author Catharina Kober with the LegioTyper-chip.
(Photo: Jonas Bemetz / TUM)

Microarray rapid test speeds up detection in case of a Legionella pneumophila outbreak

[22.03.2018] In an outbreak of Legionnaires' disease, finding the exact source as quickly as possible is essential to preventing further infections. To date, a detailed analysis takes days. Researchers at the Technical University of Munich have now developed a rapid test that achieves the same result in about 35 minutes. [more...]

Breakthrough for peptide medication

Cyclic hexapeptide in its bioactive form with the integrin-binding tripeptide sequence arginine-glycine-aspartic acid (Image: Michael Weinmueller / TUM)

The “Holy Grail” of peptide chemistry: Making peptide active agents available orally

[21.02.2018] Peptides, short amino acid chains that control many functions in the human body, represent a billion-dollar market, also in the pharmaceutical industry. But, normally these medications must be injected. A research team led by the Technical University of Munich (TUM) has now determined how peptides can be designed so that they can be easily administered as a liquid or tablet. [more...]