Persönlicher Status und Werkzeuge

Department of Chemistry

The Department of Chemistry at the Technische Universität München has taken great efforts to meet the requirements of a rapidly changing scientific environment.
We offer a broad diversity of subjects: The traditional areas of Inorganic Chemistry, Organic Chemistry, and Physical Chemistry have been enriched by Chemical Technology, Radiochemistry, Food Chemistry, Theoretical Chemistry, and Hydrochemistry many years ago. The last years saw new expansions into the fields of Biochemistry and Construction Chemistry. [More...]

Prefabrication principles: One of the three forms of the protein complex Sip1 is built-up by 32 identical subunits
image: Tilly Fleckenstein / TUM

A protein provides emergency aid

Small heat shock proteins ensure that other proteins do not clot, allowing the cell to survive stress. Defects in these “small helpers” are associated with medical conditions like cataracts and cancer. Now, scientists at the Technische Universität München (TUM) have characterized a small heat shock protein responsible for embryonic development in the Caenorhabditis elegans nematode. Presumably, a similar protein exists also in humans. [more ...]

Publikation:

Tilly Fleckenstein, Andreas Kastenmüller, Martin Lorenz Stein, Carsten Peters, Marina Daake, Maike Krause, Daniel Weinfurtner, Martin Haslbeck, Sevil Weinkauf, Michael Groll, Johannes Buchner:

The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes

Molecular Cell 58,1-12, June 18, 2015 – DOI: 10.1016/j.molcel.2015.04.019